Advances in Local Ablation Strategies for Treating Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis

Rizky Dimasyah Putra Wahab; Setiadi Drajad Kurniawan; Jonathan Overian Buon; Nadhifa Tanesha Aufazhafarin

doi:10.55927/eajmr.v4i10.407

Authors

Rizky Dimasyah Putra Wahab Banyuwangi Regional General Hospital
Setiadi Drajad Kurniawan Lung Hospital Jember
Jonathan Overian Buon Doris Sylvanus Regional General Hospital
Nadhifa Tanesha Aufazhafarin Wiyung Sejahtera Hospital

DOI:

https://doi.org/10.55927/eajmr.v4i10.407

Keywords:

Lung Cancer, Non-Small Cell Lung Cancer, Cryoablation, Microwave Ablation, Survival Rates

Abstract

Lung cancer represents foremost cause of cancer-related mortality globally. Non-small cell lung cancer (NSCLC) is the most prevalent, over 85% of all lung cancer diagnoses. The literature search was performed through databases including PubMed, Scopus, Web of Science, and ScienceDirect up to September 2025. In adverse events after both procedures including pneumothorax, bronchopulmonary hemorrhage, hemoptysis, and pleural effusion events between CA and MWA group were not significant reported (p = 0.97).. CA and MWA showed comparable effectiveness due to its minimally invasiveness, providing similar response for early and advanced-stage in NSCLC with small tumor size (<3 cm). Both procedures also offered minimizing adverse events. However, CA was a longer hospitalization than MWA.

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